R-Rsolid-0.9.31-44.fc39 $H>$8 6 6_"6 3!92d LuZLd 6 uZL"5X*Q,R4sh0Dy[g%ޱKk'K@ve(Yb:B`$Eyѷ fq\Dj"{]Ӂ5Ը'eݭzrKh1h%"& BH#W4x-jD* |i#Xi€H|a+H4 =ƾj" =|T \4-&g1ݩ]}t*ӆg^KBniwqċrN0p=`0JٯI`n$kijz"nH<š,__HEꑍjWpML';B*`jEQ2 e]Fmal`>bjCT Zg7\u; O&*u /-_Q}Ȁ)Lﯳ7޼~ܞpi℡K k.#v$9#h{4;I Dwb Hg FXC! n&r冏c9H>h_ӻ TjA&cVǒAMPl@B6a~NZ) DsTmS~gWR!&$($-W3xddXRDsB0soXvBwLft%ʺ.:WANx-3'w. *x7&DQC ," Buƅ>Up{q|O& W$Y$n2h?I4F@ =I$(a!V:,&x)Zj"NSCqU ʗR),T}6pa^Tj\}6 y&aN{" f̕X'q<1\"N+Nޔ7tJ1ޤt>`> -? d   h $LP_n{ "L" " " \"  ~"  "\"""X|(8 9 :F G"H"I$"XHYT\|"]"^R bsd;e@fElHt`"u"vpw("x"y8 dhCR-Rsolid0.9.3144.fc39Quantile normalization and base calling for second generation sequencing data Rsolid is an R package for normalizing fluorescent intensity data from ABI/SOLiD second generation sequencing platform. It has been observed that the color-calls provided by factory software contain technical artifacts, where the proportions of colors called are extremely variable across sequencing cycles. Under the random DNA fragmentation assumption, these proportions should be equal across sequencing cycles and proportional to the dinucleotide frequencies of the sample. Rsolid implements a version of the quantile normalization algorithm that transforms the intensity values before calling colors. Results show that after normalization, the total number of mappable reads increases by around 5%, and number of perfectly mapped reads increases by 10%. Moreover a 2-5% reduction in overall error rates is observed, with a 2-6% reduction in the rate of valid adjacent color mis-matches. The latter is important, since it leads to a decrease in false-positive SNP calls. The normalization algorithm is computationally efficient. In a test we are able to process 300 million reads in 2 hours using 10 computer cluster nodes. The engine functions of the package are written in C for better performance.dCbuildvm-x86-09.iad2.fedoraproject.orgFedora ProjectFedora ProjectArtistic 2.0Fedora ProjectUnspecifiedhttp://rafalab.jhsph.edu/Rsolid/linuxi6863D^Dyz";Sa fx4zAAA큤A큤A큤A큤A큤A큤Ad'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'd'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../../../../usr/lib/R/library/Rsolid/libs/Rsolid.sorootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootrootR-Rsolid-0.9.31-44.fc39.src.rpmR(Rsolid)R-RsolidR-Rsolid(x86-32)@@@@@@@@@    @R(ABI)R-corelibR.solibc.so.6libc.so.6(GLIBC_2.0)libc.so.6(GLIBC_2.1.3)libc.so.6(GLIBC_2.3.4)libc.so.6(GLIBC_2.4)libhdf5.so.200rpmlib(CompressedFileNames)rpmlib(FileDigests)rpmlib(PayloadFilesHavePrefix)rpmlib(PayloadIsZstd)rtld(GNU_HASH)4.33.0.4-14.6.0-14.0-15.4.18-14.18.91d@dI@dBzc@cAb@a@a4aj@` @Fedora Release Engineering - 0.9.31-44Florian Weimer - 0.9.31-43Iñaki Úcar - 0.9.31-42Fedora Release Engineering - 0.9.31-41Iñaki Úcar - 0.9.31-40Fedora Release Engineering - 0.9.31-39Fedora Release Engineering - 0.9.31-38Orion Poplawski - 0.9.31-37Orion Poplawski - 0.9.31-36Fedora Release Engineering - 0.9.31-35- Rebuilt for https://fedoraproject.org/wiki/Fedora_39_Mass_Rebuild- Port configure script to c99- R-maint-sig mass rebuild- Rebuilt for https://fedoraproject.org/wiki/Fedora_38_Mass_Rebuild- R 4.2.1- Rebuilt for https://fedoraproject.org/wiki/Fedora_37_Mass_Rebuild- Rebuilt for https://fedoraproject.org/wiki/Fedora_36_Mass_Rebuild- Rebuild for hdf5 1.12.1- Rebuild for hdf5 1.10.7- Rebuilt for https://fedoraproject.org/wiki/Fedora_35_Mass_Rebuild  !"0.9.310.9.31-44.fc390.9.31-44.fc39  .build-id3ad8cc351b1a78a394de512698f0f836632f2a10RsolidDESCRIPTIONINDEXMetaRd.rdsdata.rdsfeatures.rdshsearch.rdslinks.rdsnsInfo.rdspackage.rdsNAMESPACERRsolidRsolid.rdbRsolid.rdxdataprop.Hs.rdahelpAnIndexRsolid.htmlRsolid.rdbRsolid.rdxaliases.rdspaths.rdshtml00Index.htmlR.cssRsolid.htmllibsRsolid.so/usr/lib//usr/lib/.build-id//usr/lib/.build-id/3a//usr/lib/R/library//usr/lib/R/library/Rsolid//usr/lib/R/library/Rsolid/Meta//usr/lib/R/library/Rsolid/R//usr/lib/R/library/Rsolid/data//usr/lib/R/library/Rsolid/help//usr/lib/R/library/Rsolid/html//usr/lib/R/library/Rsolid/libs/-O2 -flto=auto -ffat-lto-objects -fexceptions -g -grecord-gcc-switches -pipe -Wall -Wno-complain-wrong-lang -Werror=format-security -Wp,-U_FORTIFY_SOURCE,-D_FORTIFY_SOURCE=3 -Wp,-D_GLIBCXX_ASSERTIONS -specs=/usr/lib/rpm/redhat/redhat-hardened-cc1 -fstack-protector-strong -specs=/usr/lib/rpm/redhat/redhat-annobin-cc1 -m32 -march=i686 -mtune=generic -msse2 -mfpmath=sse -mstackrealign -fasynchronous-unwind-tables -fstack-clash-protection -fcf-protectioncpiozstd19i686-redhat-linux-gnudirectoryASCII textHTML documentELF 32-bit LSB shared object, Intel 80386, version 1 (SYSV), dynamically linked, BuildID[sha1]=3ad8cc351b1a78a394de512698f0f836632f2a10, strippedPRRRRRRRRRR https://bugz.fedoraproject.org/R-Rsolidutf-848b2f9875c4f6781749606c55b22a4fedc0dbdf9234b1f48fe35e72ee21047f681da1c56e4f46dcb8224c925fd26bbd580e0afde08b45d5ddb147edd396d2624? 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